This OCR A level Biology Resource on Gene therapy is a full lesson of learning the past, present and future of Gene therapy. It covers : The process of gene delivery and their main mechanisms vectors for gene delivery and their advantages/disadvantages Some key Trials that took place in the past their results and set backs It covers the key difference between Somatic cell gene therapy and Germ line gene therapy and what their future challenges are.

This A level Biology OCR booklet on the three types of muscles It includes: The structural and functional differences in : Involuntary/smooth muscle Cardiac muscle Voluntary/Skeletal muscle A full detailed summary table that helps with Revision

This lesson focuses on coronary heart disease and its components of diet that increase its risk: Obesity salt Fats Cholesterol make up of High dentisty Lipoproteins (HDLs) and Low density Lipoproteins (LDLs)

This full lesson Booklet is the perfect resource to inform and educate students in the most latest developments of Biology in the 21st century. The Booklet begins introducing what the advancements in DNA sequencing have done and how they have produced a large amount of processed data and information and that this has resulted in the development of a brand new are n Biology called Bioinformatics. The booklet then explains as a result of all the information gathered comparison studies have been used to look at the firstly the genome size of different organisms and the number of functional genes they possess. The booklet then demonstrates an inter species comparison study looking at Beta haemoglobin and how a single mutation can lead to disease such as sickle cell anaemia and how Bioinformatics can compare all the different species data and find similarities are closely related to each other. The resource then touches on more complex disease such as cancer and the BRCA gene. The Booklet then explains how pharmaceutical companies are using Bioinformatics to focus on SNPs and using them to make new drugs. This then follows on into the NHS current project the 100,000 genome project and how Bioinformatics will be used. The booklet finishes on two exciting future developments using Bioinformatics synthetic Biology and Proteomics.

This full interactive lesson booklet on DNA sequencing defines DNA sequencing then starts off explaining past techniques such as shot gun sequencing step by step and their associated problems. The booklet then focuses on Fredrick Sangers technique of DNA sequencing and how he first cracked the process using radioactive dideoxy nucleotides. The technique goes into detail step by step. The booklet then focuses on modern day sequencing and Next Gen sequencing. The booklet then focuses how flourescent dyes and high processing power computers have dramatically changed the rate at which DNA is sequenced. Lastly the uses of DNA sequencing have been covered

This full 10 page Booklet on plant hormones plant responses to herbivory seed germination Apical dominance Abiotic responses to stress Tropisms Tropisms historical investigations

This resource covers the OCR syllabus on PLant transport- Translocation. Firstly it defines what translocation is and then further explains the key terms of source and sink regarding the translocation of sugars. The booklet then further explains the key cells the make up the Phloem tissue, their components and functions. It then goes on to explain the content of the sieve tubes and the reason why Sucrose is transported not glucose. The resource then explains how translocation occurs using the mass flow hypothesis. It shows the key mechanism how Sucrose is loaded into the phloem using a co-transporter. The booklet then shows with clearly labelled diagrams how sucrose is moved along the phloem. The finishing page focuses on the difficult 2021 Translocation question on how glucose produced in photosynthesis is translocated to parts of the plant where glucose is metabolised and stored.

Having learned about this in my Biochemistry degree. It has now been included in the OCR A level Biology A H420 Syllabus as a kind of introduction into cellular control. Having taught this for several years I have had to make my own resource as there is very little material out on it that is relevant to A level students and the textbooks don’t explain the Biochemistry fully. The resource is a Booklet gap fill with diagrams and the teacher telling them all about the various different mechanisms that control gene expression in organisms. It covers -Gene regulation-Transcriptional control : chromatin remodelling/Histone modification / Lac operon/cAMP-Post-Transcriptional control: RNA Processing /RNA editing-Translational control : protein kinases/inhibitory proteins/inititaion factors-Post-Translational control : phosphates/amino acid modification/folding proteins/cAMP modification

A level -Biology -Plant responses Topic -Lesson on Plant responses to Herbivory This includes An introduction to Herbivory what it is and the cost to the producer The types of defences plant use including Mechanical defences -spikes, hairs, barbs etc Moving defences -specifically Mimosa Pudica Chemical defence - Alkaloids with examples Chemical defence - Phenols with examples Chemical defence - Terpenoids with examples Phenological defences - Volatile Organic compounds and Pheromones with examples links to videos on the internet and a summary

This is a A level Biology OCR Genetic Engineering Booklet that will last the whole lesson. It covers : The basic process of Genetic Engineering Methods how the gene is obtained Restriction enzymes and their Recognition sites Vectors used to get the genetic material into the desired cell

This Biology OCR A level teaching resource is a great method of teaching and revising specifically plant cloning at A level It covers: Natural Clones advantages and disadvantages of asexual reproduction Vegetative Propagation advantages and disadvantages of Vegetative Propagation Artificial Clones Grafting Cuttings Micropropagation (tissue culture) advantages and disadvantages of tissue culture Plant cloning questions

This essential booklet covers the key aspects of organisation of the nervous system which includes: The central nervous system recap of a relay neurone Diagrammatic section of a reflex arc The Peripheral Nervous system Somatic Nervous system Autonomic Nervous system How the nervous system is organised The motor pathways for the autonomic and Somatic nervous systems The sympathetic subsystems The Parasympathetic subsystems Consolidation questions

This Biotechnology booklet Introduces some key terms regarding Biotechnology and the many different uses of microorganisms in Biotechnology. The introduction of Primary and secondary metabolites and when they are produced in the microbial growth curve. There are some deep level thinking questions to challenge learners. The booklet then goes on to explain some key Biotechnological processes and the microbes involved covering : The production of food, pharmaceutical drugs, commercial enzymes and Bioremediation. The booklet then introduces industrial scale fermenters and the key factors that can affect microbial growth. The booklet contains picture of a standard fermenter and a power point resource that pupils can use to label and learn the key parts. The Booklet then briefly compares Batch and Continuous culture and the key differences between them. The last page contains the key terms of aseptic technique, asepsis and Contaminants and the results of what happens if contaminants enter in the fermenter and why asepsis is key to pure culture. Lastly the challenges faced when scaling up small scale fermenters to industrial scale.

This resource has everything needed to teach and learn about the heart at OCR A level. The booklet starts at the basic structure of the heart and the main structures of heart anatomy both internal and external. The Structure is explained using a simple gap fill activity to allow students to learn and complete the first page of the booklet. The next is labeling the external and internal structures to allow students to orientate themselves. The next part of the booklet explains the key stages in the cardiac cycle using a simple gap fill and then goes on to explain the cardiac cycle graph with clear labels of what is happening the pressure changes in the atria and ventricles. The next part of the booklet explains the initiation of the cardiac cycle how the cardiac cells are myogenic and how the natural pacemaker SAN node triggers a wave of excitation over the atria and how the AVN node triggers ventricular contraction. The last part of the booklet explains ECG graphs and what each part does and how to recognise abnormal ECG traces.

The booklet covers the difficult concept of how haemoglobin transports oxygen around the body and how the haemoglobin undergoes configurational change so that it bonds oxygen more easily after the first oxygen has joined. The booklet then introduces Oxygen dissociation curves why they are sigmoid shape and how they are made including what the partial pressures means in terms of tissues in the body. There are various amount of tasks in the booklet students are challenged to make a dissociation curve with some data and need to answer some key questions on what is happening at different parts of the graph in relation to partial pressure and haemoglobin shape. The booklet then compares haemoglobin with both myglobin the oxygen storage molecule found in muscles and foetal haemoglobin. Both have questions on what these molecules do and where they are situated on the oxygen dissociation curve graph in relation to adult haemoglobin. The booklet then introduces carbon dioxide transport in great detail and the three main methods it is transported in the blood. The booklet then finishes on the Bohr effect and how carbon dioxide affects the oxygen dissociation curve and what happens when different carbon dioxide concentrations affect haemogobin loading and unloading.

This booklet cover key methods that farmers are using to improve food production for the Human population. The booklet covers : Methods of making food production more efficient In plans using selective breeding, chemical fertilisers, pesticides, herbicides etc in animals using selective breeding and the use of antibiotics

This Booklet explores the key biological molecule of Carbohydrates exploring monosaccaharides first and then moving on to complex carbohydrates such as starch, cellulose and glycogen

This resource booklet explores the Biological importance of water to life and how the key biochemical properties of water enable life to exist on our planet.

This extremely challenging content is easily explained in the OCR Biology A level Sliding Filament Theory Booklet It includes : Skeletal muscle Histology The structure of the myofibril The structure of a sarcomere How the muscle contracts -sliding filament theory How contractions change the pattern of banding Maintenance of ATP

This introduction to Biological molecules looks at the key chemical groups found in living molecules a long with the basic summary of all the key Biological molecules found in living organisms